The American Chemical Society Division of Analytical Chemistry Graduate Fellowship Program is designed to encourage basic research in the field of analytical chemistry, to promote the growth of analytical chemistry in academic institutions and industry, and to provide recognition of future leaders in the field of analytical chemistry.
Agilent/ACS Analytical Graduate Fellowship
Trenton Peters-Clarke
Coon Lab, University of Wisconsin
During the fellowship period, I will develop and advance tandem mass spectrometry methods for more efficient analysis of negatively charged analytes. The comprehensive sequence and modification characterization of RNA therapeutics, acidic proteins, O-glycosylated peptides, and endogenously modified transcripts and DNA has been limited by a lack of efficient negative-mode dissociation methods. My fundamental development and application of negative electron transfer dissociation (NETD) promises to address some of these gaps.
Eli Lilly and Company/ACS Analytical Graduate Fellowship
Julia Townsend
Marty Lab, University of Arizona
During the fellowship period, I will build upon methods using native mass spectrometry (MS) and lipoprotein nanodiscs to characterize the oligomeric states and lipid specificities of viroporins. Viroporins are small viral membrane proteins involved at multiple stages of infection, including budding, replication, assembly, and uncoating. Developing methods for better characterizing hydrophobic, fragile, and polydisperse samples for native MS will help to reveal the mechanisms of oligomerization of viroporins and may ultimately enable the development of improved viral therapeutics.
Pittcon/ACS Analytical Graduate Fellowship
Ronald Emmons
Gionfriddo Lab, University of Toledo
During the term of this fellowship, separation methods will be developed and optimized for the microextraction and chromatography of emerging environmental pollutants. The ionization mechanisms of per- and polyfluoroalkyl substances via DART will be elucidated and a screening method applicable to on-site analysis will be developed. Moreover, analytical challenges related to the analysis of underivatized cyanobacterial neurotoxins, such as beta-Methylamino-L-alanine and its isomers, will be overcome by a convenient approach involving selective solid phase microextraction (SPME) coupled to liquid-chromatography/mass spectrometry.
Pittcon/ACS Analytical Graduate Fellowship
Dylan Tabang
Li Lab, University of Wisconsin
My research is focused on developing the multiomic mass spectrometry toolbox for pancreatic and digestive disease research. My past projects have focused on using electrostatic repulsion-hydrophilic interaction chromatography to study protein glycosylation and phosphorylation simultaneously and on studying these post-translational modifications in the human pancreatic extracellular matrix. During the fellowship period, I will develop methods to perform multiomic analyses specifically of pancreatic islets of Langerhans in diabetes using liquid chromatography-mass spectrometry and mass spectrometry imaging.